Kirby Lane near Sledmere is closed and the air ambulance is in attendance after a serious road traffic accident.
Two fire engines and several police cars are also at the scene where initial reports say a car left the road and crashed into a ditch.
A spokesperson for Humberside Police said: “The incident involved a blue coloured Rover which came off the road and overturned.
“A woman driving the Rover has sustained injuries and is being taken to hospital for treatment.
“A road closure is in place while the police and other emergency services are in attendance.”